| George W. Wood | 1840 |
| Joseph Morgan | 1841 and 1842 |
| Henry Lotz | 1843 |
| John M. Wallace | 1844 |
| Dr. Merchant W. Huxford | 1845 - 1849 |
| William Stewart | 1849 - 1852 1855 - 1857 |
| Dr. Philip G. Jones | 1852 |
| Charles Whitmore | 1853 and 1854 |
| Samuel S. Morss | 1857 - 1859 |
| Franklin P. Randall | 1859 - 1864 1869 - 1873 |
| Judge James L. Worden | 1865 |
| Benjamin Saunders | 1866 |
| Henry Sharp | 1867 and 1868 |
| Col. Charles Zollinger | 1873 - 1885 1893 |
| Charles F. Muhler | 1885 - 1889 |
| Daniel L. Harding | 1889 - 1893 |
| Henry F. Scherer | 1894 1897 - 1901 |
| Chauncey B. Oakley | 1894 - 1897 |
| Henry C. Berghoff | 1901 - 1905 |
| William J. Hosey | 1906 - 1910 |
| Jesse Grice | 1910 - 1914 |
| William J. Hosey | 1914 - 1918 |
| Sherman Cutshall | 1918 - 1922 |
| William J. Hosey | 1922 - 1926 |
| William C. Geake | 1926 - 1930 |
| William J. Hosey | 1930 - 1934 |
| Harry W. Baals | 1934 - 1947 |
| Henry Branning | 1948 - 1951 |
| Harry W. Baals | 1952 - 5/9/1954 |
| Robert Meyers | 1954 - 1959 |
| Paul Mike Burns | 1960 - 1963 |
| Harold S. Zeis | 1964 - 1971 |
| Ivan Lebamoff | 1972 - 1975 |
| Robert Armstrong | 1976 - 1979 |
| Winfield Moses | 1980 - 7/8/1985 |
| Cosette Simon | 7/8/1985 - 7/19/1985 |
| Winfield Moses | 7/20/1985 - 1987 |
| Paul Helmke | 1988 - 1999 |
| Graham Richard | 2000 - 2007 |
| Tom Henry | 2008 - 3/28/2024 |
| Karl Bandemer | 3/29/2024 - 4/23/2024 |
| Sharon Tucker | 4/23/2024 - current |
- Meet the Mayor
- Fort Wayne Mayors